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The Symptoms of Opioid Withdrawl.pdf2.11 MB Why withdrawals? Prolonged and habitual use of opioids can alter the brain and lead to physical dependence. Over time, the body develops a tolerance to the drug—it needs ever-increasing amounts in order to function normally. When someone with a physical dependency quits using painkillers, the body must adapt. The result is withdrawal, which gives rise to a range of psychological and physical symptoms.

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